When green algae "can’t breathe",
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Haemoglobin an old protein in a new look

In the human body,
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You Will Have a Good Time While Buying Discount Oreo 5s, says Prof. Thomas Happe from the Work Group Photobiotechnology. Nature has produced a large number of related proteins which fulfil different functions. The green alga Chlamydomonas reinhardtii has what is known as a "truncated" haemoglobin, the function of which was previously unknown. Happe’s team has deciphered its role in surviving in an oxygen free environment.

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When Chlamydomonas has no oxygen available,
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A haemoglobin and nitric oxide help green algae to survive

The scientists studied the haemoglobin protein and its genetic blueprint in more detail using molecular biological and biochemical analyses. "One thing became clear very quickly",
Outlet Store Online To Buy Cheap Air Jordan 5 Fire Red 2013, says Dr. Anja Hemschemeier from the Work Group Photobiotechnology. "Algae in which we switched this gene off could hardly grow without oxygen." From previous studies it is known that in many organisms, haemoglobin detoxifies nitric oxide, because an overdose of this gas poisons the cells. The biologists therefore tested whether green algae which are no longer able to form haemoglobin after genetic manipulation die of nitric oxide poisoning. Their expectations: the green algae should fare better if the gas is removed using a chemical scavenger. "Surprisingly, then the algae were not able to grow at all", says Hemschemeier. The researchers concluded that,
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Nitric oxide signals: "no oxygen,
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Nitric oxide acts in many living organisms as a signalling molecule apparently also in green algae. Experiments in vitro have shown that the green algal haemoglobin interacts with nitric oxide. When the researchers artificially introduced the gas to the single cell organisms,
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, and that our haemoglobin is involved in this process", Happe sums up. His team wants to go on exploring the role of this protein in green algae,
Sale Online Authentic Air Jordan 3 Retro Black Flip, as the biologists have discovered another eleven haemoglobin genes in the organism. "Now things are really getting going", says the Bochum scientist. "The map of haemoglobin research has many blank spots that we want to fill with content. The fact that a single cell requires twelve haemoglobin proteins indicates that these fulfil finely tuned functions in the cell."

A. Hemschemeier, M. Dner,
Find Great Deals Here Air Jordan 12 Low Retro Taxi 2011, D. Merchant, M. Winkler, T. Happe (2013): Hypoxic survival requires a 2 on 2 hemoglobin in a process involving nitric oxide, Proceedings of the National Academy of Sciences,
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